It backs up your entire site (database, themes, plugins, uploads, settings) and then sends it off to Amazon S3’s low cost industrial strength storage.
You can set it to run automatically or trigger it manually as you like. It will even clean up old backups.
It does not support multi-site yet – but hopefully it will soon.
One note of caution – the automated backup jobs are triggered by wp_cron. This can be problematic for low traffic sites. You may wish to setup a cron job to visit your site at regular intervals to insure that wp_cron gets triggered regularly.
Thanks Dan and Mel!
Download WordPress Backup